Explore our diverse portfolio of high-purity botanical powders manufactured under strict global compliance standards.
Icariin is a flavonol glycoside compound extracted from several plant species in the Epimedium genus, commonly referred to as Horny Goat Weed or Yin Yang Huo in traditional Chinese medicine. As a premier China Icariin Powder Supplier, Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) has dedicated over two decades to refining the extraction, isolation, and standardization of this potent bioactive molecule.
From a molecular standpoint, Icariin (C33H40O15) acts as a natural phosphodiesterase type 5 (PDE5) inhibitor, making it a highly sought-after ingredient in formulations targeting cardiovascular health, endothelial function, and male vitality. Beyond this pathway, recent preclinical and clinical research demonstrates that Icariin plays a crucial role in bone density maintenance, neuroprotection, and cellular longevity, establishing it as a cornerstone molecule for modern anti-aging and nootropic formulations.
Our standardized Icariin powder is available in various concentrations—ranging from 10%, 20%, 40%, 50%, 60%, to ultra-pure 98% HPLC—allowing formulators to customize dosage and efficacy profiles for dietary supplements, functional beverages, and cosmetic applications.
Analyzing the market dynamics, supply chain stability, and regulatory requirements driving the global demand for Epimedium-derived Icariin.
The global market for plant-based active ingredients has experienced exponential growth, with Icariin leading the sector of natural vitality and cognitive enhancers. In North America and Europe, the shift away from synthetic compounds toward natural alternatives has placed high-purity Icariin powder at the forefront of premium dietary supplement formulations. Meanwhile, in the Asia-Pacific region, its integration into functional foods and traditional wellness remedies continues to expand rapidly.
However, the global supply chain faces challenges regarding raw material quality, pesticide residues, and heavy metal contamination. As a vertically integrated manufacturer, TRB mitigates these risks by controlling the supply chain from wild-harvested and cultivated Epimedium geographical zones in China directly to our GMP-certified extraction facilities. This ensures consistent batch-to-batch quality, price stability, and uninterrupted supply for our global partners.
How we support global brands with tailored ingredient solutions across multiple commercial sectors.
Standardized Icariin (10% to 50%) is widely formulated into capsules, tablets, and softgels targeting male health, athletic performance, and nitric oxide production. We provide custom particle sizing and density adjustments to match your specific encapsulation machinery requirements.
Leveraging our deep focus on brain health, TRB supplies low-dose, high-bioavailability Icariin powder optimized for synergistic blending with other cognitive enhancers like Alpha GPC and Kava Root Extract. These blends support neuroplasticity, memory retention, and mental clarity.
For instant drink mixes, energy shots, and functional teas, we offer water-soluble Epimedium extracts. Through advanced membrane filtration and spray-drying technologies, we minimize the natural bitter taste of the herb while maintaining full bioactive potency.
At Nanjing Tong Rui Bio-Tech (TRB), our extraction process is designed to maximize the yield and purity of Icariin while preserving the natural synergistic co-factors present in the Epimedium leaf. Our technical route includes:
Looking to the future, our R&D team is pioneering enzymatic conversion techniques to transform lower-potency flavonoids within Epimedium into high-value Icariin and Icaritin, significantly reducing production costs and environmental impact while increasing bioavailability.
Discover how different industries leverage our Icariin powder to address specific consumer health needs.
Icariin acts as an estrogen receptor phytoestrogen mimic, promoting osteoblast differentiation and mineralized bone matrix formation. It is highly recommended for postmenopausal health formulations and joint support supplements aimed at preventing osteoporosis.
By reducing oxidative stress, inhibiting acetylcholinesterase (AChE), and promoting neurite outgrowth, Icariin is integrated into premium brain health stacks. It helps protect neurons from amyloid-beta induced toxicity, supporting long-term cognitive health.
Icariin stimulates the expression of endothelial nitric oxide synthase (eNOS), leading to increased nitric oxide production. This mechanism relaxes blood vessels, improves blood flow, and supports healthy blood pressure levels, making it ideal for pre-workout and cardiovascular formulas.
Sourcing botanical extracts internationally requires rigorous adherence to local regulatory frameworks. TRB ensures that every shipment of Icariin powder complies with the destination country's import regulations, including FDA requirements in the United States and EFSA guidelines in Europe.
Our production facilities are fully certified with GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER Certificates. We provide comprehensive documentation packages with every batch, including:
Additionally, we offer localized support through our logistics partners, ensuring seamless customs clearance, DDP shipping options, and local warehousing solutions to minimize lead times.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) is a leading China-based manufacturer and exporter of premium herbal extracts and their derivatives, boasting over 20 years of industry-leading expertise. As a technology-driven enterprise, TRB integrates research and development, state-of-the-art production, and global sales channels under one roof.
Our product portfolio spans high-quality Herbal Extracts, Sweeteners, Nootropics, Vegetable & Fruit Juice Powders, Essential Oils, and Bee Products. Due to our rapid development and dedication to quality, we were honored with the prestigious 2026 Global Biotechnology and Life Sciences Award as the "Best Global Herbal Extract Provider 2026".
TRB operates three specialized factories: one dedicated to herbal extracts, one for bee products, and another for animal-derived extracts. Our focus in recent years has centered on the research and development of advanced Nootropics, Anti-Aging, and Longevity ingredients, receiving outstanding feedback from clients worldwide.
Get authoritative answers to common questions regarding sourcing, quality, and applications of Icariin Powder.
High-quality botanical ingredients manufactured to meet the highest international standards.
Get in touch with our technical sales team today for customized quotes, free samples, and regulatory documentation support.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
86-25-52863298
86-13770771528
