Explore our premium grade raw materials manufactured under strict GMP compliance for global distribution.
CDP Choline (Cytidine 5'-diphosphocholine), commonly known as Citicoline, is a naturally occurring mononucleotide that serves as a critical intermediate in the biosynthesis of structural phospholipids in cell membranes, particularly phosphatidylcholine. Upon oral administration or ingestion, CDP Choline undergoes rapid hydrolysis into its two main components: cytidine and choline. These compounds cross the blood-brain barrier and are re-synthesized in the brain to support cognitive function, cellular repair, and neurotransmitter synthesis.
As a leading Wholesale CDP Choline Powder Manufacturer & Factory, we produce high-purity Citicoline that directly feeds the Kennedy pathway. This biochemical pathway is responsible for maintaining neuronal membrane integrity. By supplying both choline (a precursor to acetylcholine) and cytidine (which converts to uridine, supporting synaptic plasticity), CDP Choline offers dual-action cognitive support. Unlike standard choline sources, Citicoline provides a highly bioavailable form of choline that avoids the typical gastrointestinal degradation associated with lower-tier choline salts.
Leveraging advanced biotechnology, robust supply chains, and international quality standards.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) is a premier, technology-based manufacturer and exporter of high-quality herbal extracts, nootropics, and nutritional raw materials. With over 20 years of industry experience, TRB has established itself as a reliable global supplier, combining state-of-the-art research and development with large-scale industrial manufacturing.
Our CDP Choline production facilities in China leverage significant structural advantages:
TRB's dedication to excellence was recognized with the prestigious 2026 Global Biotechnology and Life Sciences Award: "Best Global Herbal Extract Provider 2026".
Understanding the macro forces shaping the demand for high-quality cognitive enhancers.
With an aging global population, the demand for dietary supplements that support memory, focus, and overall brain longevity has skyrocketed. CDP Choline is a cornerstone ingredient in healthy-aging formulations.
Students, professionals, and gamers are increasingly seeking clean, crash-free cognitive enhancers. CDP Choline provides sustained mental energy without the jittery side effects of caffeine or stimulants.
Modern supplement brands are moving away from single-ingredient products. CDP Choline is highly compatible with other active ingredients like Alpha GPC, Phosphatidylserine, and adaptogenic herbal extracts.
CDP Choline's versatile physical properties and high stability make it suitable for a wide range of product formats across different global markets:
Sourcing raw materials at an industrial scale requires more than just a quality product; it demands a robust operational framework. TRB provides end-to-end solutions for multinational brands:
1. Full Regulatory Compliance & Documentation: We supply comprehensive documentation packages, including COA, MSDS, Allergen Statements, Non-GMO Declarations, and heavy metal testing reports. Our factories hold GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER Certificates, ensuring smooth customs clearance in the US, Europe, and Asia-Pacific regions.
2. Custom Particle Size & Micronization: Depending on your final dosage form, we can customize the mesh size of our CDP Choline powder. Our standard mesh is optimized for encapsulation, but we also offer micronized options for liquid suspensions and instant drink mixes.
3. Flexible Packaging & Secure Logistics: Standard packaging is 25kg fiber drums with double food-grade polyethylene inner bags. We offer customized packaging configurations for trial batches and work with top-tier logistics providers to ensure temperature-controlled, secure transit.
Get authoritative answers to technical, commercial, and regulatory questions regarding bulk CDP Choline sourcing.
Our CDP Choline (Citicoline) powder is manufactured to meet a minimum purity standard of 99.0% on a dry basis, verified by High-Performance Liquid Chromatography (HPLC). We provide batch-specific Certificates of Analysis (COA) with every shipment.
While both are premium choline donors that cross the blood-brain barrier, they follow different metabolic pathways. Alpha GPC is more direct in increasing acetylcholine levels, making it popular for acute physical and mental performance. CDP Choline (Citicoline) provides cytidine (which converts to uridine) alongside choline, making it highly effective for long-term brain cell membrane repair, structural integrity, and sustained cognitive support.
TRB operates three state-of-the-art factories certified under GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER standards. This ensures our products meet the strict import requirements of major global markets.
Our standard MOQ for commercial orders is 25kg (one full drum). However, for new customers looking to perform pilot runs or formulation testing, we can accommodate smaller sample quantities upon request.
Our CDP Choline powder has a shelf life of 24 months from the date of manufacture when stored in its original unopened packaging. It should be kept in a cool, dry place away from direct sunlight, moisture, and heat.
Yes, TRB provides comprehensive OEM/ODM services. We can premix CDP Choline with other active ingredients (such as herbal extracts, vitamins, or other nootropics) according to your specific formulation requirements, saving you processing steps in your own facility.
Expand your product line with our certified botanical and nutritional ingredients.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
Phone: 86-25-52863298
Mobile: 86-13770771528
Fax: 86-25-52867040 
