As a leading raw material pioneer, Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) provides a broad spectrum of highly standardized botanical extracts that synergize optimally with Kaempferol formulations.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) stands as a prominent pioneer and global benchmark in the production, extraction, and standardization of high-quality botanical active principles. Spanning over 20 years of relentless research and development, TRB operates at the confluence of biochemistry, industrial biotechnology, and global supply logistics.
Our company prides itself on standardizing complex plant secondary metabolites. We synthesize and extract pure molecular structures, such as the crucial flavonoid Kaempferol, designed for functional integration in anti-aging nutraceuticals, cytoprotective pharmacological agents, and cutting-edge cosmetics. TRB is proud to be named the recipient of the 2026 Global Biotechnology and Life Sciences Award — "Best Global Herbal Extract Provider 2026".
TRB operates three specialized manufacturing plants. Our primary herbal extraction facility utilizes advanced solvent extraction, column chromatography, supercritical fluid extraction, and vacuum concentration. The second facility focuses entirely on highly purified bee products, while our third plant specializes in high-purity animal bioactive molecules.
By scaling operations across these plants, we ensure strict segregation, zero cross-contamination, and high throughput. Our manufacturing pipeline meets international regulatory criteria, supported by GMP, ISO, HACCP, ORGANIC (USDA & EU), FDA Registration, HALAL, and KOSHER Certificates. These credentials ensure seamless customs verification and regulatory approval for our clients worldwide.
Kaempferol (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) is a natural tetrahydroxyflavone widely recognized for its robust therapeutic profile. When sourcing Kaempferol for large-scale operations, purity levels, chemical characterization, and solvent residues are critical parameters.
Our high-purity Kaempferol (up to 98% by HPLC-DAD/MS) undergoes extensive quality control. We perform systematic testing including High-Performance Liquid Chromatography (HPLC) assays, Nuclear Magnetic Resonance (NMR) spectroscopy, and Mass Spectrometry (MS) to verify structural integrity.
Kaempferol acts as an intracellular signal regulator. It targets key cell-survival pathways, downregulates inflammation (via NF-κB suppression), and inhibits cellular aging. This makes it an ideal ingredient for longevity and cellular health formulations.
We adhere strictly to USP <467> guidelines for residual solvents. We run raw materials through multi-screen gas chromatography (GC-MS) to detect and eliminate any trace organophosphates, heavy metals (Pb, As, Cd, Hg), or aflatoxins.
| Specification Parameter | Methodology / Standard | Guaranteed Certificate Level |
|---|---|---|
| Active Assay (Kaempferol content) | HPLC-DAD / Standard Reference Reference Materials | Standardized to ≥ 10% up to ≥ 98.0% Pure Crystalline Powder |
| Residual Solvents (USP <467>) | Gas Chromatography - Mass Spectrometry (GC-MS) | Ethanol < 5000 ppm, Methanol < 3000 ppm, Hexane Free |
| Heavy Metals Limit (Pb, As, Cd, Hg) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Pb < 1.0 ppm, As < 1.0 ppm, Cd < 0.1 ppm, Hg < 0.1 ppm |
| Pesticide Residues Screen | GC-MS/MS & LC-MS/MS Multi-Residue Analysis | Complies with EP & USP limit protocols (EC No 396/2005) |
| Microbiological Criteria | USP <61> / USP <62> Culture Media Tests | Total Plate Count < 1000 cfu/g, Yeast & Mold < 100 cfu/g, E. Coli Negative |
Nanjing Tong Rui Bio-Tech (TRB) capitalizes on China's robust botanical supply chain. We secure vast cultivation zones for natural source materials like Sophora japonica, Camellia sinensis, and other rich flavonoid precursors. This stable supply chain insulates our clients from seasonal variations and raw material price volatility.
By consolidating processing facilities in strategic locations and utilizing energy-efficient dual-extraction lines, we achieve significant economies of scale. We pass these savings directly to our clients, offering competitive wholesale prices without compromising batch quality, stability, or purity.
Our strategic proximity to key transit hubs like Shanghai, Shenzhen, and Ningbo ensures efficient logistics. Whether shipping via air freight for urgent pharmaceutical needs or ocean freight for bulk contract manufacturing, TRB provides consistent delivery timelines globally.
Navigating import barriers requires robust documentation and technical validation. TRB simplifies local customs and regulatory approvals by providing a comprehensive suite of compliance documents.
We provide Drug Master Files (DMF), Technical Construction Files (TCF), allergen declarations, non-GMO statements, BSE/TSE-free certificates, and comprehensive MSDS reports to streamline registration with agencies like the FDA, EFSA, and TGA.
Our teams align with Foreign Supplier Verification Programs (FSVP). We maintain continuous communication with customs brokers, ensuring smooth transit through US and European ports with minimal delay.
Kaempferol is oxygen and light-sensitive. We protect all bulk products inside food-grade vacuum-sealed double LDPE liners inside heavy-duty fiber drums. This preserves stability under shifting cargo temperatures.
Kaempferol's therapeutic profile makes it a key ingredient in many high-growth markets. Below are the primary application sectors where our clients formulate with TRB Kaempferol.
As a potent senolytic agent, Kaempferol helps clear senescent cells, reduce chronic low-grade inflammation, and mitigate age-related muscle degeneration. It is widely formulated into lifespan-extension supplements.
Recent studies demonstrate Kaempferol's ability to cross the blood-brain barrier. It helps lower neuro-inflammation and protect dopaminergic neurons, making it a valuable addition to brain health formulas.
Thanks to its strong antioxidant profile, Kaempferol helps inhibit collagenase and elastase. This protects skin structures from UV-induced degradation, driving its popularity in clean-label anti-aging cosmetics.
To address bioavailability challenges, TRB is at the forefront of formulation technology. We develop advanced lipid-carrier matrices, self-emulsifying drug delivery systems (SEDDS), and micro-encapsulation techniques that significantly improve Kaempferol absorption in human clinical trials.
Expand your product formulations with our diverse catalog of natural botanical extracts and functional juice powders.
Get in touch with our technical sales team for specification documents, sample evaluations, and custom pricing.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
86-25-52863298
86-13770771528
86-25-52867040
