Explore our premium selection of highly purified extracts and active compounds manufactured under strict GMP compliance.
For more than 20 years, Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) has stood at the forefront of global biotechnology, serving as a premier China-based manufacturer and exporter of high-purity herbal extracts, nootropics, and active pharmaceutical ingredients (APIs). Our commitment to scientific excellence and rigorous quality control has positioned us as a trusted partner for multi-national brands across the Americas, Europe, and the Asia-Pacific region.
Recognizing the paradigm shift in consumer demand toward longevity, cellular health, and cognitive enhancement, TRB has invested heavily in the research, development, and large-scale synthesis of NADH (Reduced Nicotinamide Adenine Dinucleotide). As a critical coenzyme in cellular respiration and ATP production, NADH represents the next frontier in metabolic health and anti-aging formulations.
Our dedication to advancing biotechnology was globally recognized when we were honored with the prestigious 2026 Global Biotechnology and Life Sciences Award as the "Best Global Herbal Extract Provider 2026".
An analytical overview of market dynamics, supply chain requirements, and the growing demand for high-stability coenzymes.
The global market for NAD+ precursors and derivatives is experiencing exponential growth. Unlike standard NAD+, NADH (Reduced Form) carries high-energy electrons directly into the mitochondrial electron transport chain, making it highly sought after for premium cognitive and physical performance formulations.
Historically, the industrial application of NADH was limited by its extreme sensitivity to moisture, light, and thermal degradation. TRB's advanced microencapsulation and crystallization techniques have solved these stability bottlenecks, enabling long-term storage and versatile formulation options.
As a leading manufacturer, TRB bridges the gap between raw material synthesis and finished product manufacturing. Our optimized logistics network ensures that temperature-controlled, high-purity NADH is delivered seamlessly to dietary supplement and pharmaceutical brands worldwide.
How TRB achieves industry-leading purity and stability through advanced biocatalytic and crystallization technologies.
Unlike traditional chemical synthesis which relies on harsh organic solvents and generates toxic byproducts, TRB utilizes a proprietary multi-enzyme cascade system. This biocatalytic pathway mimics natural cellular processes to synthesize NADH from high-grade precursors, ensuring a highly bio-compatible, eco-friendly, and residue-free final product.
Following synthesis, the crude NADH solution undergoes multi-stage industrial chromatography. We utilize specialized ion-exchange and size-exclusion resins to isolate the active beta-NADH isomer from alpha-isomers and degradation products, consistently achieving HPLC purity levels exceeding 98% (and up to 99.5% for pharmaceutical grades).
To prevent rapid oxidation and hydrolysis, the purified NADH is subjected to a controlled freeze-drying (lyophilization) process. We introduce food-grade protective matrices (such as specific sugar alcohols or acid-resistant polymers) that shield the NADH molecules, resulting in a free-flowing powder with significantly enhanced shelf-life and thermal resistance.
Tailoring NADH solutions to meet diverse regulatory standards and consumer preferences across global markets.
North American & European Markets (Nootropics & Anti-Aging): In these regions, NADH is highly demanded in sublingual tablets, enteric-coated capsules, and sustained-release formulations. Because stomach acid can degrade NADH, TRB provides specialized enteric-coated granules that bypass the stomach, maximizing absorption in the small intestine.
Asia-Pacific Market (Functional Beverages & Beauty): The demand for beauty-from-within and instant energy solutions has driven the integration of stable NADH into liquid shots and powder sachets. TRB offers highly soluble, taste-masked NADH grades suitable for ready-to-mix beverage formulations.
Cosmetic & Topical Applications: Emerging research highlights NADH's role in skin cell rejuvenation and protection against UV-induced oxidative stress. TRB supplies ultra-fine, cosmetic-grade NADH optimized for topical creams, serums, and anti-aging skincare lines.
Operating under global regulatory frameworks to guarantee safety, traceability, and consistency.
TRB operates three specialized manufacturing facilities designed to meet the highest international standards. Our dedicated herbal extract factory, bee product factory, and animal extract facility are equipped with state-of-the-art cleanrooms, automated synthesis lines, and advanced analytical laboratories.
To ensure seamless entry into global markets, our manufacturing processes and facilities are fully certified by international governing bodies. Our compliance portfolio includes:
Every batch of NADH undergoes comprehensive testing, including HPLC for purity, ICP-MS for heavy metals, GC-MS for residual solvents, and microbiological assays. We provide full COA (Certificate of Analysis) and third-party laboratory verification upon request.
End-to-end B2B services designed to accelerate your product development and optimize your supply chain.
We offer custom blending services, combining NADH with complementary active ingredients such as Coenzyme Q10, NMN, Melatonin, or customized botanical extracts like Rosemary and Gotu Kola to create synergistic, market-ready formulas.
From raw powder supply to finished product packaging, TRB provides comprehensive OEM/ODM solutions. We can manufacture bulk powder, premixes, capsules, tablets, and customized packaging formats tailored to your brand identity.
Navigating international regulatory landscapes can be complex. TRB provides comprehensive documentation support, including DMF (Drug Master Files), technical dossiers, stability study data, and safety certifications to streamline your registration process.
Technical and commercial insights to assist your procurement and product development teams.
High-quality botanical extracts and active compounds designed to support cognitive health, longevity, and metabolic wellness.
A leading global developer and manufacturer of high-purity botanical extracts, nootropics, and active ingredients. Empowering health and wellness brands worldwide with science-backed solutions.
Fax: 86-25-52867040