Brown yellow powder with characteristic odor and taste
GMO Status
GMO Free
Packing
In 25kgs fiber drums
Storage
Keep container unopened in cool, dry place. Keep away from strong light.
Shelf Life
24 months from date of production
Apple Extract Phloridzin: Natural Support for Glucose Metabolism and Antioxidant Protection
Product Overview
Phloridzin, a unique polyphenolic compound found exclusively in apples (Malus domestica), is extracted from organic, high-quality apple cultivars using advanced acetone-mediated or ethanol-based methods to ensure optimal purity and potency. This natural ingredient is renowned for its multifaceted health benefits, including glucose regulation, anti-glycation effects, and antioxidant support, making it ideal for nutraceuticals, functional foods, and skincare formulations.
Key Benefits
Glucose Metabolism Support
Phloridzin inhibits sodium-glucose cotransporters (SGLT1 and SGLT2), reducing intestinal glucose absorption and renal glucose reabsorption. This mechanism helps maintain healthy blood sugar levels within the normal range, particularly beneficial for metabolic health. Clinical studies highlight its role in managing diabetic and obesity-related conditions by mimicking the action of pharmaceutical SGLT2 inhibitors, with a Ki value of 39 nM for SGLT2.
Anti-Glycation & Antioxidant Properties
Phloridzin traps reactive methylglyoxal (MGO) and glyoxal (GO), preventing the formation of advanced glycation end products (AGEs) linked to aging and chronic diseases. It also boosts the antioxidant enzyme paraoxonase by up to 23%, reducing lipid peroxidation and inflammation.
Cardiovascular and Cancer Prevention
Regular apple polyphenol intake correlates with reduced risks of cardiovascular disease and certain cancers (e.g., colorectal, breast). Phloridzin synergizes with apple fiber to modulate bile acid metabolism, further supporting colorectal health.
Skin Health
Used in cosmetics, phloridzin enhances antioxidant defenses without stimulating melanogenesis at recommended concentrations, ensuring safety for anti-aging formulations.
Applications
Dietary Supplements
Capsules (e.g., 600 mg AppleWise® extracts) for metabolic and antioxidant support.
Functional Foods
Added to beverages, juices, and snacks to enhance nutritional profiles.
Skincare
Integrated into serums and creams to combat oxidative stress and glycation-induced skin damage.
Scientific Validation
Source Optimization
Phloridzin content varies by apple cultivar, with russeted varieties (e.g., Golden Russet) containing up to 978.8 µg/g in peels—significantly higher than standard cultivars.
Safety
GRAS (Generally Recognized As Safe) status for food and cosmetic use, with no adverse effects reported at therapeutic doses.
Why Choose Our Phloridzin?
Organic Sourcing
Derived from certified organic apples, free from pesticides and heavy metals.
Third-Party Tested
Guaranteed purity (>95% polyphenols) and compliance with international standards.
Customizable Formats
Available as powder (43.6 mg/mL in ethanol), capsules, or liquid extracts for diverse formulations.
Keywords
Apple polyphenols, Phloridzin benefits, natural SGLT2 inhibitor, anti-glycation agent, organic apple extract, glucose metabolism support, skincare antioxidants.
Frequently Asked Questions
What is Phloridzin and where is it sourced from?
Phloridzin is a unique polyphenolic compound found exclusively in apples (Malus domestica). Our Phloridzin is extracted from organic, high-quality apple cultivars using advanced acetone-mediated or ethanol-based methods to ensure optimal purity and potency.
How does Apple Extract Phloridzin support glucose metabolism?
Phloridzin acts as a natural SGLT2 inhibitor. It works by inhibiting sodium-glucose cotransporters (SGLT1 and SGLT2), which reduces intestinal glucose absorption and renal glucose reabsorption, helping to maintain healthy blood sugar levels.
What are the anti-glycation and antioxidant benefits of Phloridzin?
It traps reactive methylglyoxal (MGO) and glyoxal (GO) to prevent the formation of advanced glycation end products (AGEs) linked to aging. Additionally, it boosts the antioxidant enzyme paraoxonase by up to 23%, reducing lipid peroxidation and inflammation.
Is Phloridzin safe for cosmetic and skincare applications?
Yes, Phloridzin has GRAS (Generally Recognized As Safe) status. In cosmetics, it enhances antioxidant defenses and combats glycation-induced skin damage without stimulating melanogenesis at recommended concentrations.
What product formats and purity levels are available?
Our Apple Extract Phloridzin is third-party tested to guarantee over 95% polyphenols. It is available in customizable formats including powder, capsules, and liquid extracts (43.6 mg/mL in ethanol) to suit diverse formulation needs.
