Established as a pioneering force in the global biotechnology landscape, Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) has served as China's leading manufacturer and exporter of highly standardized herbal extracts and their functional derivatives for over 20 years. Our foundation is built on combining intensive research and development, smart production pipelines, and specialized international market logistics.
By blending modern biotechnology with pure nature, our products span Herbal Extracts, Sweeteners, Nootropics, Vegetable & Fruit Juice powders, Essential Oils, and Bee Products. As a testament to our quality dedication, we have been recognized with the prestigious 2026 "Global Biotechnology and Life Sciences Award" as the "Best Global Herbal Extract Provider 2026".
Arachidonic Acid (ARA), a critical omega-6 polyunsaturated fatty acid (PUFA, 20:4n-6), has evolved from a niche specialty compound into a foundational nutrient in global health, wellness, and clinical nutrition. Historically extracted from animal tissues, the modern commercial scale relies almost exclusively on precision fermentation technologies using the filamentous fungus Mortierella alpina. This shift has unlocked highly pure, vegan-friendly, and contamination-free ARA Oils and Powders suitable for sensitive food applications globally.
Currently, the global Arachidonic Acid market is experiencing a significant Compound Annual Growth Rate (CAGR), driven by the strict regulations requiring DHA and ARA pairing in infant formulas worldwide. The European Food Safety Authority (EFSA), the US Food and Drug Administration (FDA), and China’s National Health Commission (NHC) have continuously updated food safety standards, elevating the requirement for high-stability, contaminant-free ARA sources. In the industrial sphere, China has emerged as the premier global hub for ARA manufacturing, leveraging advanced fermentation infrastructures, strong supply chains, and superior refining technologies to fulfill international demand.
Moving away from animal-source extraction to pure Mortierella alpina cultivation, guaranteeing sustainable, allergen-free, and vegan-certified compounds.
Advanced microencapsulation structures protecting fragile double bonds against oxidation, extending stability in dry powder matrices.
Complete elimination of heavy metals, plasticizers, and organic solvents, adhering to international regulations for infant nutrition.
Developing high-quality Arachidonic Acid requires navigating complex lipid oxidation pathways. As an unsaturated fatty acid with four double bonds, ARA is highly sensitive to heat, light, and oxygen. The technical roadmap implemented by TRB combines biological engineering with mechanical physical barrier technologies to deliver stable bio-available formats.
The manufacturing process begins with the mutation and cultivation of high-yield Mortierella alpina strains. Through precise carbon-to-nitrogen ratio control in fermentation tanks, the mycelium accumulates high concentrations of intracellular lipids rich in Arachidonic Acid. Automated aeration and temperature control systems prevent the creation of unwanted saturated fatty acids, keeping the final lipid composition consistent across batches.
To convert ARA Oil into a cold-water-dispersible powder, we utilize secondary microencapsulation technology. Utilizing a wall material matrix of starch, gelatin, or vegetarian gums, the oil droplets are dispersed at the sub-micron scale using high-pressure homogenization. Spray drying under nitrogen atmosphere wraps these droplets inside a solid shell, keeping oxygen out and extending shelf life to up to 24 months at room temperature.
Through physical winterization and molecular distillation, free fatty acids, volatile odor compounds, and pigment residues are removed. This produces a clear, golden ARA oil with a neutral taste profile, ensuring it does not alter the sensory properties of the final milk powder or functional food products.
"Innovative microencapsulation shields the delicate polyunsaturated structure of Arachidonic Acid, transforming unstable oil into a durable, cold-water-soluble powder suitable for global distribution."
Arachidonic Acid plays multiple vital physiological roles, requiring different formulations depending on target applications and regional regulations:
Operating as a global manufacturer involves more than just offering high-quality ingredients; it requires providing robust supply chain solutions that address regulatory and logistics challenges. TRB’s macro industry solutions focus on three key pillars:
TRB currently operates three specialized manufacturing facilities: one dedicated to herbal extraction, one for bee products, and a third optimized for animal-derived active compounds. Our production setups are designed to prevent cross-contamination and meet the highest global standards.
As consumer preferences shift toward cleaner formulas, TRB has focused on developing nootropics and longevity ingredients, such as Brain Health Herb Extracts, Anti-Aging Herb Extracts, and Longevity Herb Extracts, which have received positive feedback from our international clientele.
Exported to over 60 countries and regions, TRB’s biological compounds support international brands in infant nutrition, dietary supplements, and pharmaceuticals. We remain committed to the research and development of clean, high-performance plant and microbial extracts, supporting human health worldwide.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
Fax: 86-25-52867040
