Explore our premium selection of certified herbal extracts, nutraceuticals, and functional food powders manufactured under strict global quality standards.
A comprehensive look into the science, extraction methodologies, and physiological benefits of this powerful lipid-lowering compound.
Polycosanol (commonly spelled as Policosanol) is a natural mixture of long-chain aliphatic alcohols (ranging from 24 to 34 carbon atoms) extracted primarily from plant waxes. The most prominent source is sugarcane wax (Saccharum officinarum), though it can also be isolated from beeswax, rice bran, and wheat germ. The primary active component within this mixture is Octacosanol (C28), which typically accounts for 60% to 65% of the total alcohol content, accompanied by other beneficial alcohols such as Triacontanol (C30) and Hexacosanol (C26).
As global demand for natural cardiovascular support and cholesterol management solutions intensifies, Polycosanol has emerged as a cornerstone ingredient in the functional food and dietary supplement sectors. By modulating cholesterol synthesis in the liver and enhancing the degradation of low-density lipoprotein (LDL) cholesterol, Polycosanol offers a clinically backed, natural alternative to synthetic lipid-regulating agents.
Clinical studies indicate that Policosanol supports healthy lipid profiles by inhibiting HMG-CoA reductase, the key enzyme involved in cholesterol biosynthesis, and increasing LDL receptor activity.
Octacosanol, the major constituent of Polycosanol, has been shown to improve oxygen utilization during exercise, enhance physical stamina, and reduce muscle recovery times in athletes.
Emerging research suggests that long-chain alcohols may exhibit cytoprotective properties, supporting cellular health and mitigating oxidative stress within the central nervous system.
A Legacy of Excellence in Botanical Extraction and Global Supply Chain Integration.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB), is the China Leading manufacturer and exporter of herbal extracts and its derivatives for more than 20 years.
TRB is a technology-based company that combines research and development, production and international market sales. TRB products include the Herbal extracts, Sweeteners, Nootropics, Vegetable & Fruit Juice powder, Essential oil, Bee Products.
Thanks to TRB's rapid development and dedicated service in the plant extract industry over the years, we have been awarded the 2026 "Global Biotechnology and Life Sciences Award" - ''Best Global Herbal Extract Provider 2026''
TRB currently has three factories: one is a herbal extract factory, the second is a bee product factory, and the third is dedicated to animal extract products. Our production facilities hold a comprehensive suite of international quality credentials, including GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER Certificates.
In recent years, TRB has focused heavily on the research and development of Nootropics products, such as Brain Health Herb Extract, Anti-Aging Herb Extract, and Longevity Herb Extract, receiving exceptional feedback from our global clientele.
We manufacture Polycosanol to meet the most stringent pharmaceutical and nutraceutical standards globally.
| Analysis Item | Specification (Sugarcane Wax Source) | Specification (Beeswax Source) | Test Method |
|---|---|---|---|
| Appearance | White to off-white crystalline powder | Light yellow to white powder | Visual |
| Total Aliphatic Alcohols | ≥ 90.0%, ≥ 95.0%, ≥ 98.0% | ≥ 90.0% | GC (Gas Chromatography) |
| Octacosanol Content | ≥ 60.0% | ≥ 10.0% - 15.0% | GC-FID |
| Loss on Drying | ≤ 1.0% | ≤ 1.5% | USP <731> |
| Heavy Metals (as Pb) | ≤ 10 ppm | ≤ 10 ppm | ICP-MS |
| Arsenic (As) | ≤ 1.0 ppm | ≤ 1.0 ppm | ICP-MS |
| Total Plate Count | ≤ 1,000 cfu/g | ≤ 1,000 cfu/g | USP <61> |
| Yeast & Mold | ≤ 100 cfu/g | ≤ 100 cfu/g | USP <61> |
How TRB's Polycosanol addresses global health trends and industrial requirements across major markets.
With exports spanning over 60 countries, TRB adapts its Polycosanol formulations to comply with regional regulatory frameworks, including US FDA NDIs, European EFSA guidelines, and Asian pharmacopoeias.
We provide tailored particle sizes (micronized powders for enhanced absorption) and oil-soluble liquid formulations to meet the specific processing demands of tablet compression, hard-shell encapsulation, and functional beverages.
Operating three dedicated manufacturing facilities allows TRB to guarantee year-round inventory stability. Our vertical integration from raw agricultural wax sourcing to final purification mitigates market price volatility.
How global brands incorporate TRB Polycosanol into high-performance consumer products.
Dietary Supplements: Widely utilized in cardiovascular health formulations, often combined with Red Yeast Rice, Coenzyme Q10, or Phytosterols to create synergistic lipid-lowering profiles.
Sports Nutrition: Incorporated into pre-workout formulations and stamina-boosting capsules. The high Octacosanol content supports glycogen storage in muscles and optimizes oxygen utilization during high-intensity training.
Cosmetics & Skincare: Beeswax-derived Policosanol is utilized in premium topical creams and balms for its emulsifying properties and its ability to reinforce the skin's natural lipid barrier, preventing trans-epidermal water loss.
Driving innovation through green chemistry and advanced biotechnology.
Supercritical CO2 Extraction: TRB is transitioning its primary extraction lines to Supercritical Fluid Extraction (SFE) technology. This eliminates organic solvent residues entirely, providing an ultra-pure, eco-friendly product that meets the cleanest label requirements.
Bioavailability Enhancement: We are currently developing nano-emulsion and micro-encapsulation delivery systems to overcome the hydrophobic nature of long-chain aliphatic alcohols, significantly increasing their absorption rate in the human digestive tract.
Sustainable Sourcing: By partnering directly with organic sugarcane agricultural cooperatives in Southern China, we ensure a fully traceable, socially responsible, and carbon-minimized raw material supply chain.
Expert answers to common technical, regulatory, and commercial inquiries regarding Polycosanol supply.
Sugarcane-derived Polycosanol contains a higher concentration of Octacosanol (typically 60% to 65%), which is the primary active compound studied for cardiovascular health and cholesterol management. Beeswax-derived Policosanol has a different distribution of aliphatic alcohols (with lower Octacosanol ratios) and is frequently preferred in cosmetic applications and specific dietary supplement formulations targeting physical endurance.
We utilize advanced vacuum crystallization and multi-stage purification processes. Every batch is tested using Gas Chromatography (GC) head-space analysis to guarantee that solvent residues are well below the strict limits defined by the USP, EP, and ChP pharmacopoeias.
TRB's factories are fully certified under GMP, ISO 9001, ISO 22000 (HACCP), USDA Organic, EU Organic, FDA facility registration, Halal, and Kosher. This comprehensive certification suite ensures our ingredients are ready for seamless integration into products destined for any global market.
Our standard packaging is 25 kg fiber drums lined with double-layer food-grade polyethylene bags. For evaluation and formulation trials, our standard MOQ starts at 1 kg. Customized packaging options are available upon request for contract manufacturing partners.
Yes, we provide complete regulatory support documentation, including Certificate of Analysis (COA), Allergen Statements, Non-GMO Declarations, BSE/TSE-Free Certificates, MSDS, and detailed process flowcharts required for FDA NDI or European novel food notifications.
Discover our extensive portfolio of high-purity extracts and fruit powders designed to elevate your product formulations.
Whether you require technical specifications, custom packaging, or a bulk quotation, our global sales and scientific support teams are ready to assist you.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
86-25-52863298
86-13770771528
86-25-52867040
Get direct factory pricing and technical documentation for your formulation requirements.
Inquire Now
