For more than 20 years, Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) has reigned as a premier Chinese manufacturer, developer, and global exporter of high-potency herbal extracts, natural derivatives, and critical metabolic active components. Guided by clinical utility, bio-chemical stabilization, and pure process engineering, TRB provides essential building blocks to the global health and wellness industries.
TRB operates at the intersection of rigorous research, strict industrial-scale manufacturing, and compliant international supply. Our diverse ingredient portfolio spans Herbal extracts, Sweeteners, Nootropics, Vegetable & Fruit Juice powders, Essential oils, and Bee Products.
As a testament to our ongoing breakthroughs in active compound stability and bio-processing systems, TRB has been honored with the prestigious 2026 "Global Biotechnology and Life Sciences Award" as the ''Best Global Herbal Extract Provider 2026''.
Coenzyme Q10 (CoQ10) is a crucial fat-soluble quinone structure within cellular mitochondria. Sourcing it at scale requires sophisticated engineering platforms to resolve bioavailability constraints and secure uniform product yields.
Moving beyond traditional chemical synthesis, TRB utilizes optimized strains of Rhodobacter sphaeroides and modified Saccharomyces cerevisiae. This bio-fermentation process produces 100% trans-isomer CoQ10, mimicking the natural molecule without harmful organic residue.
We manage the transformation balance between oxidized Ubiquinone and reduced Ubiquinol. Ubiquinol offers superior bioavailability but degrades rapidly. TRB utilizes nitrogen blanket isolation and liposome carriers to prevent degradation and guarantee product stability.
Pure CoQ10 is naturally hydrophobic. We resolve this limitation through advanced spray-drying microencapsulation. Using clean-label carrier matrices, we create a highly stable, water-dispersible CoQ10 powder (10% & 20% concentration) ideal for functional beverages and liquid formulas.
The next horizon of CoQ10 extraction revolves around metabolic flux analysis (MFA) and non-carrier nanostructured lipid systems. TRB's research pipelines are currently focusing on carbon-neutral fermentation cycles and zero-solvent supercritical CO2 crystallization techniques. These advances will lower manufacturing footprints while raising the biological absorption limits of final consumer products.
Global brand requirements for Coenzyme Q10 vary by sector. We provide tailored solutions to simplify formulation steps and speed up product launch timelines.
Reliability in manufacturing depends on precise execution, raw material access, and advanced automated process controls.
Our fermentation tanks use real-time sensors to track dissolved oxygen levels, pH curves, and nutrient consumption rates, ensuring consistent batch-to-batch yields.
We avoid harsh hydrocarbon solvents by using food-safe ethanol crystallization columns, achieving high purity without toxic chemical trace residues.
With three dedicated factories (herbal extracts, bee products, and animal-derived extraction), TRB manages independent supply networks to protect clients from supply shocks.
Years Industry Leadership
Dedicated GMP Factories
Countries Exported To
Active Assay Purity
Navigating regulatory environments is a primary hurdle for global brand sourcing. TRB supports international clients with a complete compliance framework that simplifies customs entry and audit validation.
Our production facilities hold complete documentation, including GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER Certificates. We provide detailed Drug Master Files (DMF), technical dossiers, heavy metal limits analysis, and allergen certifications for every shipment.
Additionally, we supply custom particle size distribution (PSD) options, bulk density adaptations, and targeted pesticide screening to meet stringent FDA and EFSA requirements.
For sourcing managers and raw material buyers, unit cost is only one factor. TRB focuses on minimizing the overall cost of ownership through reliable risk mitigation.
We run automated warehouse storage protocols alongside buffer inventory programs, safeguarding supply continuity for contract manufacturers during peak production periods.
Inconsistent particle sizes can lead to flowability issues and poor blending. We provide standardized milled profiles to ensure consistent tableting and encapsulating run rates.
Every batch undergoes Inductively Coupled Plasma Mass Spectrometry (ICP-MS) testing to confirm heavy metal levels remain well within USP, EP, and Proposition 65 thresholds.
Technical answers to key product, chemical, and logistics questions from professional procurement teams.
Our CoQ10 has a verified shelf life of 24 to 36 months when stored in original, unopened drums. It must be kept away from direct sunlight, moisture, and temperatures exceeding 25°C. For Ubiquinol, we pack with nitrogen flushing to prevent oxidation.
We use microbial fermentation using select bacterial and yeast strains. This ensures the output is 100% natural trans-isomer, matching the biology of human CoQ10, without the synthetic cis-isomer residues found in lower-grade alternatives.
Yes. Our mechanical milling and air classification systems allow us to adjust particle size distributions from standard crystals to fine micronized powders (down to D90 < 10 microns) to suit your specific tableting or liquid carrier needs.
We provide full documentation, including GMP, ISO, HACCP, ORGANIC, FDA facility registration, HALAL, and KOSHER certifications, along with complete COAs and batch-specific heavy metal and residual solvent reports.