Explore our certified, high-performance active ingredients sourced and manufactured under strict GMP conditions.
Polydatin (also known as piceid), a natural precursor and glucoside of resveratrol, is rapidly emerging as a cornerstone ingredient in the global health and wellness sectors. Primarily extracted from the roots of Polygonum cuspidatum (Giant Knotweed), Polydatin offers distinct biochemical advantages over free resveratrol, notably its superior water solubility, enhanced stability against enzymatic degradation, and higher oral bioavailability. As a leading wholesale polydatin powder manufacturer and factory, Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) is at the forefront of supplying this high-demand molecule to global markets.
Unlike resveratrol, which is highly susceptible to rapid metabolism and oxidation, Polydatin features a glucose moiety attached to its structure. This glycosylation not only increases its solubility in aqueous environments but also allows it to be absorbed via active glucose transporters in the intestine, leading to significantly higher systemic concentrations.
Scientific research highlights Polydatin's multi-targeted pharmacological properties, including potent antioxidant, anti-inflammatory, cardioprotective, and neuroprotective activities. It acts as a powerful SIRT1 activator, making it a premier candidate for anti-aging and longevity formulations.
The global demand for natural active ingredients has shifted from basic herbal powders to highly purified, standardized phytochemicals. Polydatin is experiencing a surge in commercial interest due to several key macroeconomic and scientific drivers:
| Specification / Grade | Purity (HPLC) | Primary Application | Key Regulatory Compliance |
|---|---|---|---|
| Nutraceutical Grade | ≥ 98.0% | Dietary Supplements, Anti-aging Capsules, Nootropic Blends | FDA Registered, Kosher, Halal, Non-GMO |
| Cosmetic Grade | ≥ 98.0% | Skin Whitening, Anti-wrinkle Creams, UV Repair Serums | INCI Registered, Low Heavy Metals, Low Odor |
| Pharmaceutical Grade | ≥ 99.0% | Clinical Research, API Intermediates, Therapeutic Formulations | GMP Compliant, EP/USP Standards, Ultra-low Impurities |
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB) is a leading China-based manufacturer and exporter of premium herbal extracts and their derivatives, boasting over 20 years of industry expertise. We combine cutting-edge research and development, state-of-the-art production facilities, and international sales networks to deliver top-tier botanical solutions globally.
Our dedication to quality and innovation has earned us the prestigious 2026 Global Biotechnology and Life Sciences Award as the "Best Global Herbal Extract Provider 2026". We operate three specialized factories dedicated to herbal extracts, bee products, and animal-derived extracts, ensuring absolute control over the supply chain.
Our facilities are fully certified under international standards, including GMP, ISO, HACCP, ORGANIC, FDA, HALAL, and KOSHER. We specialize in high-purity active ingredients, including Nootropics, Brain Health Extracts, and Longevity Herb Extracts, providing customized solutions for clients in over 60 countries.
How TRB leverages advanced technology to guarantee consistent quality, competitive pricing, and uninterrupted supply.
Our factories utilize closed-loop, automated countercurrent extraction systems. This ensures maximum yield of Polydatin from raw Polygonum cuspidatum while minimizing solvent waste and energy consumption, translating directly to cost savings for our wholesale partners.
Equipped with advanced analytical instruments such as HPLC, GC-MS, and ICP-MS, our in-house QC laboratory tests every batch for purity, heavy metals, pesticide residues, and solvent residues to ensure strict compliance with USP, EP, and ChP standards.
We prioritize eco-friendly manufacturing. By using water and food-grade ethanol as extraction solvents, we eliminate toxic chemical residues. Our waste treatment systems recycle water and organic waste, aligning with global corporate sustainability goals.
How global brands integrate our high-purity Polydatin Powder into successful consumer products.
In the Western nutraceutical market, Polydatin is formulated into cellular health and anti-aging supplements. It is frequently combined with other longevity ingredients such as NMN (Nicotinamide Mononucleotide), Coenzyme Q10, and Quercetin. Manufacturers leverage its high bioavailability to claim superior efficacy over standard resveratrol formulations.
Recommended Dosage: 50mg to 250mg per capsule/tablet daily.
In East Asia, Polydatin is highly sought after for skin-brightening and hyperpigmentation-correcting formulations. Because it inhibits tyrosinase activity and reduces melanin synthesis, it is incorporated into premium whitening essences, sheet masks, and night creams. Its anti-inflammatory properties also make it suitable for sensitive skin formulations.
Recommended Concentration: 0.5% to 2.0% in topical formulations.
Technical, commercial, and logistical answers for procurement managers and product developers.
High-quality ingredients designed to meet the rigorous demands of global manufacturing.
Get in touch with our technical sales team today for custom quotes, specification sheets, and sample requests.
Pioneer Bio-Park, No 127 North Road Xishan Bridge, Yu Hua Tai District, Nanjing, China 210012
86-25-52863298
86-13770771528
86-25-52867040
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