Standardized botanical extracts optimized for Japanese regulatory compliance and high bioavailability formulations.
Standardized Polyphenols & Chicoric Acid for immune modulation and systemic anti-inflammatory support.
Rich in Sinensetin and Rosmarinic Acid, supporting renal health and reducing inflammatory joint swelling.
High-purity Silymarin (HPLC/UV) for hepatoprotective pathways and oxidative stress mitigation.
Standardized Eleutherosides B+E, enhancing stress resilience and reducing chronic inflammatory fatigue.
Navigating the intersection of Kampo tradition, an aging demographic, and strict health food regulations.
Japan represents one of the most sophisticated and demanding markets for botanical extracts globally. Driven by a rapidly aging population (super-aging society) and a deeply rooted cultural acceptance of preventive medicine, the demand for high-quality anti-inflammatory herb extracts has surged. In Japan, chronic inflammation is recognized as a precursor to joint degradation, cognitive decline, and metabolic disorders. Consequently, local manufacturers of dietary supplements, functional foods, and cosmetics are actively seeking reliable raw material suppliers who can deliver consistent, standardized, and highly bioavailable active compounds.
The industrial landscape in Japan is characterized by the strict separation of pharmaceutical-grade ingredients and food-grade materials. The transition towards the Foods with Function Claims (FFC - 機能性表示食品) system since 2015 has allowed companies to make specific health claims supported by scientific evidence. To successfully enter this market, anti-inflammatory extracts must not only meet high purity standards but also possess robust scientific documentation, including clinical trials or comprehensive systematic reviews (SR) that prove their efficacy in human subjects.
How we guarantee seamless clearance through Japan Customs and the Ministry of Health, Labour and Welfare (MHLW).
We provide comprehensive documentation including detailed manufacturing flowcharts, allergen statements, and BSE/TSE-free declarations required by the Pharmaceuticals and Medical Devices Agency (PMDA) and MHLW for food and pharmaceutical additives.
Utilizing advanced GC-MS/MS and LC-MS/MS testing, we screen every batch of our anti-inflammatory herb extracts against Japan's Positive List System, ensuring zero-detectable levels of prohibited agricultural chemicals.
Japanese importers demand exceptionally low microbial counts. Our state-of-the-art steam sterilization technology allows us to meet strict microbiological limits (Total Plate Count < 1,000 cfu/g, Coliforms Negative) without degrading active compounds.
Our quality control laboratory is equipped with high-performance liquid chromatography (HPLC), gas chromatography (GC), and atomic absorption spectroscopy (AAS) to verify active ingredient concentrations and guarantee the absence of heavy metals. We understand that in Japan, quality is not just a specification; it is a promise of safety and reliability. By aligning our production processes with Japanese Good Manufacturing Practices (GMP), we ensure that our partners receive raw materials that require no additional purification or testing upon arrival at Japanese ports.
A leading global manufacturer and exporter of herbal extracts and derivatives for over 20 years.
Nanjing Tong Rui Bio-Tech Co., Ltd. (TRB), is the China Leading manufacturer and exporter of herbal extracts and its derivatives for more than 20 years.
TRB is a technology-based company that combines research and development, production and international market sales. TRB products include the Herbal extracts, Sweeteners, Nootropics, Vegetable & Fruit Juice powder, Essential oil, Bee Products.
TRB's rapid development and dedicated service in the plant extract industry over the years, we have been awarded the 2026 "Global Biotechnology and Life Sciences Award" - ''Best Global Herbal Extract Provider 2026''
TRB currently has three factories, one is a herbal extract factory, the other is a bee product factory and the another is for animal extract products, and the factory has a series of certificates such as GMP, ISO, HACCP, ORGANIC, FDA, HALAL, KOSHER Certificates.
In recent years, TRB has focused on the research and development of Nootropics products, such as Brain Health Herb Extract, Anti-Aging Herb Extract, Longevity Herb Extract which have good feedback from our customers.
Leveraging geographic proximity, advanced extraction technology, and cost-efficiency.
Partnering with a China-based manufacturer like TRB offers significant strategic advantages for Japanese trading companies and brand owners. The geographic proximity between China and Japan translates to shorter transit times, lower shipping costs, and reduced carbon footprints compared to sourcing from Europe or North America. Shipments from our Nanjing facility can reach major Japanese ports (Tokyo, Yokohama, Osaka, Kobe) within 3 to 5 days, enabling agile inventory management and just-in-time manufacturing.
Furthermore, our large-scale production capacity allows us to offer highly competitive pricing without compromising on quality. We source raw botanicals directly from GAP-certified cultivation bases across China, ensuring complete traceability and raw material security. By implementing advanced extraction technologies such as supercritical CO2 extraction, membrane filtration, and low-temperature vacuum concentration, we achieve higher yields and preserve the delicate bioactive profiles of anti-inflammatory herbs.
How our anti-inflammatory extracts are integrated into popular Japanese consumer products.
Incorporated into soothing serums, anti-acne lotions, and sensitive skin formulations to reduce redness and UV-induced micro-inflammation.
Formulated alongside glucosamine and chondroitin to target joint pain, osteoarthritis, and mobility issues in Japan's senior demographic.
Water-soluble anti-inflammatory extracts integrated into ready-to-drink (RTD) health teas, promoting daily metabolic and immune wellness.
Explore our full range of certified raw materials manufactured under strict GMP standards.
High-purity joint health active, widely used in Japanese joint support formulations.
Organic sulfur compound supporting joint mobility and reducing exercise-induced inflammation.
Premium hydrolyzed collagen peptides for skin elasticity and joint matrix repair.
High-grade emulsifier and source of phosphatidylcholine for cognitive formulations.
Rich in glycogen, taurine, and zinc, supporting liver function and vitality.
Pharmaceutical-grade bile acid derivative for digestive and biliary support.
Traditional botanical extract supporting healthy blood glucose levels.
High-purity bile acid used in lipid emulsification and pharmaceutical research.
Natural anticoagulant peptide supporting healthy blood circulation.
Fibrinolytic enzyme complex supporting cardiovascular health and blood flow.
Nutrient-rich extract widely used in J-Beauty anti-aging and skin brightening products.
Specialized compound for biochemical research and advanced formulations.
Addressing technical, regulatory, and logistics queries from Japanese procurement managers.